The pathological conditions of hypersecretion of liquids, such as Ménière’s Syndrome, and defecation disorders (diarrhoea) affecting the gastrointestinal tract, are characterized by an excessive release of liquids (specifically endolymph and perilymph) at the level of the apparatuses involved in the specific pathology.
These diseases are not yet fully understood and consequently there is no definitive remedy which is effective for everyone: the therapy is based on the attempt to alleviate the symptoms.
BIOS, always focused on rare diseases or those with low prevalence where there is a strong medical need that has not been completely satisfied, offers some solutions aimed at the management of the symptoms.
Related diseases
Diarrhoea
The pathological condition of hypersecretion can be found in the intestinal tract, in the context of symptoms such as diarrhoea.
The solutions proposed by BIOS for this pathological condition are produced based on Antisecretory Factor (AF), a protein that modulates the transport of water and ions.
The discovery of Antisecretory Factor dates back to 1984. At that period researchers had observed that this protein was able to inhibit the hypersecretion of liquids inside the intestinal lumen caused by the cholera toxin.
Antisecretory Factor is present in the cells of all tissues but is particularly abundant in the intestinal mucosa. It acts by blocking the chlorine channels which, when excessively activated, cause hypersecretion in the intestinal lumen.
Specific dietary approaches lead to increased levels of Antisecretory Factor and, therefore, to improving the symptoms of the hypersecretion of liquids.
Ménière’s Disease
Among the pathological conditions of hypersecretion of liquids is Ménière’s disease, which is characterized by symptoms such as auricular fullness, tinnitus (whistling, buzzing, internal pulsations in the ear), dizziness and hearing loss.
It is now almost certain that the symptoms are due to an increase in fluid (endolymph and perilymph) in the inner ear, with a consequent increase in pressure.
The solutions proposed by BIOS for this pathological condition are based on Antisecretory Factor (AF), a protein that modulates the transport of water and ions.
The discovery of Antisecretory Factor dates back to 1984. At that period researchers had observed that this protein was able to inhibit the hypersecretion of liquids inside the intestinal lumen caused by the cholera toxin.
Antisecretory Factor is present in the cells of all tissues but is particularly abundant in the intestinal mucosa. It acts by blocking the chlorine channels which, when excessively activated, cause hypersecretion in the intestinal lumen.
Specific dietary approaches lead to increased levels of Antisecretory Factor and, therefore, to improving the symptoms of the hypersecretion of liquids.